An
estimated 2 billion people in the developing world suffer from the effects of
micronutrient malnutrition, caused primarily by poor quality diets which are
characterized by high food staple (e.g. rice) intakes. Inadequate intakes of
essential vitamins and minerals lower disease resistance, increases mortality,
compromise cognitive development, stunt growth, and lower work productivity.
Preschool children and mothers of reproductive age are most vulnerable due to
their higher requirements.
The
density of minerals and vitamins in food staples eaten widely by the poor may
be increased through plant breeding - a process known as biofortification.
Biofortification can be accomplished through conventional plant breeding or
through use of transgenic techniques. The density of trace minerals in food
staples may also be increased through the use fertilizers "fortified" with
these trace minerals.
HarvestPlus
seeks to develop and distribute varieties of food staples (rice, wheat, maize,
cassava, pearl millet, sweetpotato, and beans) which are high in iron, zinc,
and provitamin A through an interdisciplinary, global alliance of now more than
100 scientific institutions and implementing agencies, working in 42 developing
and developed countries. Biofortification demands the application of
interdisciplinary research representing plant breeding, molecular biology,
human nutrition, food science, farm extension, communications, and economics.
Biofortified
crops offer a rural-based intervention that, by design, initially reach these
more remote populations, which comprise a majority of the undernourished in
many countries, and then extend to urban populations as production surpluses
are marketed. In this way, biofortification complements fortification and
supplementation programs, which work best in centralized urban areas and then
reach into rural areas only in areas with good infrastructure. Initial
investments in agricultural research at a central location can generate high
recurrent benefits at low cost as adapted biofortified varieties become
available in country after country across time at low recurrent costs.
In
broad terms, three things must happen for biofortification to be successful.
First, the breeding must be successful - high nutrient density must be combined
with high yields and high profitability. Second, efficacy must be demonstrated
- the micronutrient status of human subjects must be shown to improve when
consuming the biofortified varieties as normally consumed. Thus, sufficient
nutrients must be retained in processing and cooking and these nutrients must
be sufficiently bioavailable. Third, the biofortified crops must be adopted by
farmers and consumed by those suffering from micronutrient malnutrition.
Biofortified crops must be just as productive/profitable as competing varieties
which are not biofortified.